If your players are combat monsters, don't run it for them. There's actually rather little combat in the adventure, as most of it is puzzles or traps that take very specific means (ie not just a FART roll) to disable/overcome. To repeat what was said above, EGG wrote it as a reply to the "My character is 36th level and has +5 swords of everything so I must be a badass D&D player!" mentality of the time. Gygax was big on player skill in the game as opposed to a PC's power level and ToH reflects this to the nines.
If your players are ok with the above, or just playing it for the intellectual challenge, or just for laughs then go ahead.
On a side note, there was a podcast a while back where a guy tried to repeat the "Ready Player One" challenge. That is, he was playing AD&D and had a copy of the module to reference....but he only had 1 character!
Dunno if he ever finished it, but was making good progress.
PS: The recently published "D&D Art and Arcana" book/set has a print copy of the original "Horrible Tomb" Gary ran at Origins; the prototype of what would become the Tomb of Horrors. I haven't read it yet, but look forward to the differences with the TSR published module.